diff --git a/lib/dp-packet.h b/lib/dp-packet.h
index bddaa2b5d..eea5a9215 100644
--- a/lib/dp-packet.h
+++ b/lib/dp-packet.h
@@ -1117,6 +1117,49 @@ dp_packet_update_rss_hash_ipv4_tcp_udp(struct dp_packet *packet)
     dp_packet_set_rss_hash(packet, hash);
 }
 
+static inline void ALWAYS_INLINE
+dp_packet_update_rss_hash_ipv6_tcp_udp(struct dp_packet *packet)
+{
+    if (dp_packet_rss_valid(packet)) {
+        return;
+    }
+
+    const uint8_t *pkt = dp_packet_data(packet);
+    const uint16_t l3_ofs = packet->l3_ofs;
+    uint32_t ipv6_src_off = offsetof(struct ovs_16aligned_ip6_hdr, ip6_src);
+    uint32_t ipv6_dst_off = offsetof(struct ovs_16aligned_ip6_hdr, ip6_dst);
+    uint32_t ipv6_proto_off = offsetof(struct ovs_16aligned_ip6_hdr,
+                                       ip6_ctlun.ip6_un1.ip6_un1_nxt);
+    const void *ipv6_src_l = &pkt[l3_ofs + ipv6_src_off];
+    const void *ipv6_src_h = &pkt[l3_ofs + ipv6_src_off + 8];
+    const void *ipv6_dst_l = &pkt[l3_ofs + ipv6_dst_off];
+    const void *ipv6_dst_h = &pkt[l3_ofs + ipv6_dst_off + 8];
+    const void *l4_ports = &pkt[packet->l4_ofs];
+    uint64_t ipv6_src_lo, ipv6_src_hi;
+    uint64_t ipv6_dst_lo, ipv6_dst_hi;
+    uint32_t ports;
+    uint32_t hash = 0;
+
+    memcpy(&ipv6_src_lo, ipv6_src_l, sizeof ipv6_src_lo);
+    memcpy(&ipv6_src_hi, ipv6_src_h, sizeof ipv6_src_hi);
+    memcpy(&ipv6_dst_lo, ipv6_dst_l, sizeof ipv6_dst_lo);
+    memcpy(&ipv6_dst_hi, ipv6_dst_h, sizeof ipv6_dst_hi);
+    memcpy(&ports, l4_ports, sizeof ports);
+
+    /* IPv6 Src and Dst. */
+    hash = hash_add64(hash, ipv6_src_lo);
+    hash = hash_add64(hash, ipv6_src_hi);
+    hash = hash_add64(hash, ipv6_dst_lo);
+    hash = hash_add64(hash, ipv6_dst_hi);
+    /* IPv6 proto. */
+    hash = hash_add(hash, pkt[l3_ofs + ipv6_proto_off]);
+    /* L4 ports. */
+    hash = hash_add(hash, ports);
+    hash = hash_finish(hash, 42);
+
+    dp_packet_set_rss_hash(packet, hash);
+}
+
 #ifdef  __cplusplus
 }
 #endif
diff --git a/lib/dpif-netdev-extract-avx512.c b/lib/dpif-netdev-extract-avx512.c
index 3b6bc62e3..4afbed97e 100644
--- a/lib/dpif-netdev-extract-avx512.c
+++ b/lib/dpif-netdev-extract-avx512.c
@@ -887,7 +887,7 @@ mfex_avx512_process(struct dp_packet_batch *packets,
 
                 /* Process UDP header. */
                 mfex_handle_ipv6_l4((void *)&pkt[54], &blocks[9]);
-
+                dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
             } break;
 
         case PROFILE_ETH_IPV6_TCP: {
@@ -910,7 +910,7 @@ mfex_avx512_process(struct dp_packet_batch *packets,
                     continue;
                 }
                 mfex_handle_tcp_flags(tcp, &blocks[9]);
-
+                dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
             } break;
 
         case PROFILE_ETH_VLAN_IPV6_TCP: {
@@ -936,7 +936,7 @@ mfex_avx512_process(struct dp_packet_batch *packets,
                     continue;
                 }
                 mfex_handle_tcp_flags(tcp, &blocks[10]);
-
+                dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
             } break;
 
         case PROFILE_ETH_VLAN_IPV6_UDP: {
@@ -957,7 +957,7 @@ mfex_avx512_process(struct dp_packet_batch *packets,
 
                 /* Process UDP header. */
                 mfex_handle_ipv6_l4((void *)&pkt[58], &blocks[10]);
-
+                dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
             } break;
         default:
             break;
diff --git a/lib/flow.c b/lib/flow.c
index 8ab9df3fc..b1e1fb34d 100644
--- a/lib/flow.c
+++ b/lib/flow.c
@@ -1019,6 +1019,8 @@ miniflow_extract(struct dp_packet *packet, struct miniflow *dst)
                     miniflow_push_be16(mf, ct_tp_dst, ct_tp_dst);
                     if (dl_type == htons(ETH_TYPE_IP)) {
                         dp_packet_update_rss_hash_ipv4_tcp_udp(packet);
+                    } else if (dl_type == htons(ETH_TYPE_IPV6)) {
+                        dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
                     }
                 }
             }
@@ -1032,6 +1034,8 @@ miniflow_extract(struct dp_packet *packet, struct miniflow *dst)
                 miniflow_push_be16(mf, ct_tp_dst, ct_tp_dst);
                 if (dl_type == htons(ETH_TYPE_IP)) {
                     dp_packet_update_rss_hash_ipv4_tcp_udp(packet);
+                } else if (dl_type == htons(ETH_TYPE_IPV6)) {
+                    dp_packet_update_rss_hash_ipv6_tcp_udp(packet);
                 }
             }
         } else if (OVS_LIKELY(nw_proto == IPPROTO_SCTP)) {